La Crosse once had a Chicago, Milwaukee, St. Paul & Pacific Railroad (Milwaukee Road) mainline and branch line, a Chicago, Burlington & Quincy Railroad (CB&Q) mainline and a Chicago & North Western Railway (C&NW) branch line. Today, the former Milwaukee Road mainline is owned by CPKC, the former CB&Q is owned by BNSF Railway and the branch lines have been reused as trails.